Neurotrophin-3-loaded multichannel nanofibrous scaffolds promoted anti-inflammation, neuronal differentiation, and functional recovery after spinal cord injury

X Sun, C Zhang, J Xu, H Zhai, S Liu, Y Xu… - ACS Biomaterials …, 2020 - ACS Publications
collagen/astrocytic scar formation limited, but the functional … as the guidance for axonal
regeneration and outgrowth, but also … slightly improved microenvironment for nerve regeneration. …

Therapeutic effect of neurotrophin-3 treatment in an injectable collagen scaffold following rat spinal cord hemisection injury

BA Breen, H Kraskiewicz, R Ronan… - ACS Biomaterials …, 2017 - ACS Publications
… and acute stages of inflammatory mediated neurodegeneration, concur with a … improved
functional recovery in additional to promoting a hospitable environment for axonal regeneration

Scaffold mediated delivery of drugs/genes for promoting nerve regeneration via gene silencing/pathway inhibition after traumatic nerve injuries

N Zhang - 2020 - dr.ntu.edu.sg
… topographical cues to enhance nerve regeneration are also … promote significant axon
regeneration and functional recovery. … of drug-loaded conduits in sciatic nerve transected rats and …

Glial-derived growth factor and pleiotrophin synergistically promote axonal regeneration in critical nerve injuries

NZ Alsmadi, GS Bendale, A Kanneganti… - Acta biomaterialia, 2018 - Elsevier
… to mediated axonal growth and partial functional recovery in … -2) and neurotrophin 3 (NT-3),
are upregulated after injury in all … multi-channel conduits are effective in nerve regeneration

[HTML][HTML] Modern trends for peripheral nerve repair and regeneration: beyond the hollow nerve guidance conduit

CR Carvalho, JM Oliveira, RL Reis - Frontiers in bioengineering and …, 2019 - frontiersin.org
… that can be used to improve peripheral nerve regeneration (PNR), … axonal regeneration with
better-quality motor functional … guided nerve tissue regeneration, multichannel NGCs have …

A hyaluronic acid/silk fibroin/poly-dopamine-coated biomimetic hydrogel scaffold with incorporated neurotrophin-3 for spinal cord injury repair

Q Sha, Y Wang, Z Zhu, H Wang, H Qiu, W Niu, X Li… - Acta Biomaterialia, 2023 - Elsevier
… Here, we adopted a mussel-inspired strategy to functionalize … to NT-3-mediated tissue
regeneration and the integration of … glial scars and enhanced nerve regeneration and myelination …

Lentiviral Gene Therapy from Multi-channel Bridges to Investigate Acute and Chronic Spinal Cord Repair

D Smith - 2019 - deepblue.lib.umich.edu
… the spinal cord microenvironment to improve functionalaxonal regeneration in the spinal
cord that is correlated with … neurotrophin 3 (NT3) to improve myelination of regenerating

[HTML][HTML] Spinal cord conduits for spinal cord injury regeneration

Y Ma, Q Chen, W Li, H Su, S Li, Y Zhu, J Zhou… - … Regeneration, 2023 - Elsevier
… precursor cells to enhance nerve regeneration and angiogenesis. … endogenous nerve
regeneration by bridging the spinal cord with … and degradability of some functional materials (eg, …

[HTML][HTML] Role and prospects of regenerative biomaterials in the repair of spinal cord injury

S Liu, YY Xie, B Wang - Neural regeneration research, 2019 - journals.lww.com
functional repair scaffolds to mimic a better regenerative … to deliver neurotrophin-3 (NT-3)
directly into the rat spinal cord … a favorable microenvironment for axonal regeneration and …

[HTML][HTML] Collagen for neural tissue engineering: Materials, strategies, and challenges

WH Huang, SL Ding, XY Zhao, K Li, HT Guo… - Materials Today Bio, 2023 - Elsevier
Multichannel collagen scaffolds as peripheral nerve conduits … of biomaterials in NTE, including
neurotrophin-3 (NT-3), fibroblast … , axonal regeneration is enhanced to achieve functional